Acetals in amidoalkylation of phosphonous carboxylic acids
The use of free phosphonous carboxylic diacids in three-component carbamate version of the Kabachnik--Fields reaction in acetyl chloride medium allows introducing acetals into the reaction sphere to result in phosphinic peptides. The employment of low-stable and functionally substituted aldehydes in the form of acetals provides phosphinic peptides that are difficult to obtain by other methods.
Authors
- Sergey V. Simonov (ORCID: https://orcid.org/0000-0002-6366-0255)
- Alexey V. Borodachev (ORCID: https://orcid.org/0000-0002-3458-5129)
- S. R. Golovash
- М. В. Дмитриев (ORCID: https://orcid.org/0000-0002-8817-0543)
- В. В. Рагулин (ORCID: https://orcid.org/0000-0002-3967-1034)
- Dmitry E Ivanov
Institutions
- Osipyan Institute of Solid State Physics RAS (RU)
- Institute of Physiologically Active Compounds (RU)
Publication Details
- Journal
- Mendeleev Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.71267/mencom.7650
- Primary Topic
- Organophosphorus compounds synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation