Structural and functional alteration of the gut microbiomes in ICU staff: a cross-sectional analysis
Our findings indicated that ICU staff exhibited a reduction in gut microbiome diversity which was associated with an increase in virulence factors and carbohydrate-active enzymes, as well as with a heightened susceptibility to endocrine and metabolic diseases and cancers.
Authors
- Lianlian Qu
- Xin Zhao (ORCID: https://orcid.org/0000-0002-4935-4809)
- Zhizhong Yu (ORCID: https://orcid.org/0000-0001-9592-9186)
- Jiaxin Xu (ORCID: https://orcid.org/0000-0002-6797-1413)
- Chenyang Dong (ORCID: https://orcid.org/0000-0002-1445-7154)
- Xing Zhao (ORCID: https://orcid.org/0000-0002-1439-6275)
- Hong Liu (ORCID: https://orcid.org/0000-0002-0896-8409)
- You Shang (ORCID: https://orcid.org/0000-0003-4097-6131)
- Hexiao Shen (ORCID: https://orcid.org/0009-0000-5142-2180)
- Yongling Lv
- Jiancheng Zhang (ORCID: https://orcid.org/0000-0002-2820-0851)
- Bing Xie
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
- Hubei University (CN)
Publication Details
- Journal
- Critical Care
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s13054-025-05379-7
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China