Generalized Pairwise Comparisons to Support Shared Decision-Making in the CODA Trial
This comparative effectiveness study of antibiotics and appendectomy illustrates that the GPC method is a flexible yet mathematically rigorous quantitative analysis of benefit-risk balance. This method provides a more exhaustive and nuanced quantitative assessment of the differences between 2 treatment modalities in terms of prioritized outcomes. Furthermore, GPC could support SDM by considering individual prioritizations of the multiple outcomes.
Authors
- Sarah E. Monsell (ORCID: https://orcid.org/0000-0002-2563-534X)
- Éric Barré
- Mickaël De Backer (ORCID: https://orcid.org/0000-0003-1669-6391)
- Samuel Salvaggio
- Jean‐Christophe Chiêm (ORCID: https://orcid.org/0000-0001-7346-5843)
- David R. Flum (ORCID: https://orcid.org/0000-0002-7288-0436)
- Everardo D. Saad (ORCID: https://orcid.org/0000-0003-4039-588X)
- Marc E Buyse (ORCID: https://orcid.org/0000-0002-4559-0994)
- Patrick J. Heagerty
Institutions
- University of Washington (US)
- International Drug Development Institute (Belgium) (BE)
- Seattle University (US)
- Hasselt University (BE)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.2484
- Citations
- 1
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 3.13