Early Serum Lipid Profile Changes after Laparoscopic Sleeve Gastrectomy at a Tertiary Care Hospital

Objective: This research aims to ascertain how frequently dyslipidemia resolves in patients having laparoscopic sleeve gastrectomy in tertiary care hospitals. Study Design: Quasi-experimental study. Settings: Department of Surgery, Allied Hospital, Faisalabad Pakistan. Duration: September 2021 to March 2022. Methods: 95 patients, aged between 20 and 50 years, who had dyslipidemia and a BMI of more than 30 kg/m2 were selected for the study. Following informed consent, patients were recruited for the study using non-probability consecutive sampling, preoperative venous blood samples taken while fasting for lipid levels and they subsequently had sleeve gastrectomy. The fasting lipid profile test was conducted after three months of surgery. The frequency at which dyslipidemia resolved was recorded. SPSS 22 was used for data entry and analysis. Using stratification, effect modifiers such as age, gender, diabetes, and BMI were managed. The post-stratification chi-square test was used to determine their impact on the result. The significance level is chosen where the P-value is equal to or less than 0.05. Results: A total of 95 patients with a mean age of 33.87± 8.6 years were registered in this research. 53.7% of the participants were women and 46.3% of men. BMI averaged 38.5±2.9 kg/m2. 83.2% of the patients had diabetes. Eighty-two percent of the patients had hypertension. 37.9% of the patients were smokers. A decrease in dyslipidemia was observed in 57.9% of the individuals. Conclusion: Most patients experience reduced hyperlipidemia load following a laparoscopic sleeve gastrectomy.