Connecting concentrations of copper, selenium, and zinc with transcriptomic and proteomic data of well-characterized human colorectal cancer cell lines
Herein we identify gene signatures associated with intracellular copper and zinc concentrations in CRC cell lines. Extrapolating these signatures to primary colorectal tumors revealed that they can inform outcome of CRC patients.
Authors
- C. Meyer
- John M. Mariadason (ORCID: https://orcid.org/0000-0001-9123-7684)
- Natalia Vukelic (ORCID: https://orcid.org/0000-0003-0123-5701)
- Anna P. Kipp (ORCID: https://orcid.org/0000-0002-3307-1038)
Institutions
- Olivia Newton-John Cancer Wellness & Research Centre (AU)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Journal of Trace Elements in Medicine and Biology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1016/j.jtemb.2025.127638
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Carl-Zeiss-Stiftung
- Deutsche Forschungsgemeinschaft