Fluoxetine Suppresses Osteosarcoma Progression<i>In Vivo</i>by Inducing Apoptosis and Inhibiting the AKT/mTOR/NF-κB Signaling Pathway
Fluoxetine demonstrates promising anti-tumor activity in OSCC by inducing apoptosis, inhibiting metastasis, and targeting oncogenic signaling pathways. These findings suggest that fluoxetine may serve as a potential therapeutic agent for OSCC, warranting further investigation for clinical application.
Authors
- Ming-Chou Ku (ORCID: https://orcid.org/0000-0002-6468-2261)
- Fei‐Ting Hsu (ORCID: https://orcid.org/0000-0002-2153-340X)
- Yu-Hsi Chen (ORCID: https://orcid.org/0009-0005-1718-6715)
- Chi-Huan Li
- Shih-Wei Liu
Institutions
- National Yang Ming Chiao Tung University (TW)
- Central Taiwan University of Science and Technology (TW)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-03-28
- DOI
- https://doi.org/10.21873/anticanres.17530
- Citations
- 2
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 2.94