Time-varying association between blood pressure and malignant brain edema after large hemispheric infarction: a prospective cohort study
In LHI patients, 24-hour mean SBP demonstrated a U-shaped association with MBE risk, with no significant effect during 1-12 h and a positive linear correlation during 13-24 h after onset. DBP exhibited a threshold effect, primarily influencing MBE risk during 1-12 h after onset.
Authors
- Wen Guo (ORCID: https://orcid.org/0000-0002-3691-4942)
- Xindi Song (ORCID: https://orcid.org/0000-0003-3718-335X)
- Yilun Deng (ORCID: https://orcid.org/0000-0002-7209-7855)
- Ming Liu (ORCID: https://orcid.org/0000-0001-9760-2806)
- Yanan Wang (ORCID: https://orcid.org/0000-0002-7144-603X)
- Meng Liu (ORCID: https://orcid.org/0000-0002-2934-7978)
Institutions
- Baylor College of Medicine (US)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Neurological Sciences
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1007/s10072-025-08147-1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China