Appropriateness of loading dose and TDM in patients treated with teicoplanin: a single-centre observational retrospective cohort study comparing single-daily and thrice-weekly regimens

Higher adherence to loading dose and TDM recommendations was observed for TWR compared with SDR. However, the TWR often failed to achieve adequate TDM levels for higher targets, highlighting the need for optimized TWR loading dose strategies.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-03-28
DOI
https://doi.org/10.1093/jac/dkaf097
Citations
1
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
1.39
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article

Appropriateness of loading dose and TDM in patients treated with teicoplanin: a single-centre observational retrospective cohort study comparing single-daily and thrice-weekly regimens

Stefania Merli, Spinello Antinori, Maddalena Matone, Andrea Giacomelli et al.
1 citations
Journal of Antimicrobial Chemotherapy
Antibiotics Pharmacokinetics and Efficacy
1.39
article

Appropriateness of loading dose and TDM in patients treated with teicoplanin: a single-centre observational retrospective cohort study comparing single-daily and thrice-weekly regimens

Stefania Merli, Spinello Antinori, Maddalena Matone, Andrea Giacomelli, Martina Gerbi, Riccardo De Giorgi, Andrea Gori, Chiara Mariani, Marta Colaneri, Stefania Piconi, Dario Cattaneo, Matteo Passerini, Alessandra Helen Behring, Martina Offer
article en
1 citations

Abstract

Higher adherence to loading dose and TDM recommendations was observed for TWR compared with SDR. However, the TWR often failed to achieve adequate TDM levels for higher targets, highlighting the need for optimized TWR loading dose strategies.

Journal of Antimicrobial ChemotherapyVol. 80(6)
University of Milan (IT), Luigi Sacco Hospital (IT), Alessandro Manzoni Hospital (IT), Centre for Multidisciplinary Research in Health Science (IT), ASST Fatebenefratelli Sacco (IT)
Good health and well-being
Openalex Percentile: Top 22%
Antibiotics Pharmacokinetics and Efficacy
1.39
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Appropriateness of loading dose and TDM in patients treated with teicoplanin: a single-centre observational retrospective cohort study comparing single-daily and thrice-weekly regimens — Stefania Merli, Spinello Antinori, et al. · Journal of Antimicrobial Chemotherapy (2025) | TGRS Research Map | TGRS