Management of congenital ichthyoses: guidelines of care: Part one: 2024 update
In 2019, a group of experts published the first European guidelines for the management of congenital ichthyoses after a multidisciplinary expert meeting held in 2016. An update of these guidelines and literature search was planned every 5 years, given the clinical, molecular and therapeutic advances, including the use of biologic therapies. We present here updated guidelines that have been developed by a reorganized multidisciplinary group of international experts. The evidence is based on a systematic review of recent literature, discussions and consensus reached at an expert conference held in June 2023. The guidelines provide summarized evidence and expert-based recommendations that aim to guide clinicians in the management of these rare and often complex diseases. These guidelines consist of two sections. This Part one covers topical and systemic therapies (including oral retinoids, biologics and Janus kinase inhibitors), future therapeutic approaches, psychosocial management, telemedicine, communicating the diagnosis and genetic counselling, prenatal diagnosis and preimplantation genetic testing.
Authors
- Á. Hernández‐Martín (ORCID: https://orcid.org/0000-0001-7260-8718)
- Carlos Gutiérrez-Cerrajero (ORCID: https://orcid.org/0000-0002-9698-2920)
- Raman Malhotra (ORCID: https://orcid.org/0000-0002-1911-6383)
- Saturnino Santos
- Kira Süßmuth (ORCID: https://orcid.org/0000-0002-7284-9949)
- I. Dreyfus (ORCID: https://orcid.org/0000-0003-1999-9312)
- Amy S. Paller (ORCID: https://orcid.org/0000-0001-6187-6549)
- Rogelio González‐Sarmiento (ORCID: https://orcid.org/0000-0002-2726-6795)
- Marie‐Anne Morren (ORCID: https://orcid.org/0000-0002-4860-5194)
- Carmen Sălăvăstru (ORCID: https://orcid.org/0000-0002-3160-9826)
- Ana Martı́nez (ORCID: https://orcid.org/0000-0002-2707-8110)
- Silvia Vendruscolo Milesi (ORCID: https://orcid.org/0000-0002-9568-6476)
- Hélène Texier
- Nathalie Jonca (ORCID: https://orcid.org/0000-0003-3602-0102)
- Eli Sprecher (ORCID: https://orcid.org/0000-0002-4093-1032)
- Andrea Diociaiuti (ORCID: https://orcid.org/0000-0003-0879-9825)
- Judith Fischer (ORCID: https://orcid.org/0000-0002-8580-8118)
- Anne Audouze
- Heiko Traupe (ORCID: https://orcid.org/0000-0001-6104-3483)
- Mandy Aldwin
- J. Mazereeuw‐Hautier (ORCID: https://orcid.org/0000-0001-6259-9790)
- Karin Veldman (ORCID: https://orcid.org/0000-0003-4410-7291)
- Kathrin Giehl (ORCID: https://orcid.org/0000-0002-0092-5164)
- Matthias Schmuth (ORCID: https://orcid.org/0000-0002-4064-1334)
- Antoni Gostyński (ORCID: https://orcid.org/0000-0002-1091-2914)
- Joanna Narbutt (ORCID: https://orcid.org/0000-0002-8135-012X)
- Céline Granier Tournier (ORCID: https://orcid.org/0000-0002-6274-0341)
- Ronaldo Morales (ORCID: https://orcid.org/0000-0002-5856-3717)
- Cristina Has (ORCID: https://orcid.org/0000-0001-6066-507X)
- Edel A. O’Toole (ORCID: https://orcid.org/0000-0002-4084-4836)
- Masashi Akiyama (ORCID: https://orcid.org/0000-0001-5863-9315)
- Hagen Ott
- Maya El Hachem
- Christine Bodemer
Institutions
- Northwestern University (US)
- Hôpital Necker-Enfants Malades (FR)
- Innsbruck Medical University (AT)
- Inserm (FR)
- University of Freiburg (DE)
- Carol Davila University of Medicine and Pharmacy (RO)
- Queen Mary University of London (GB)
- Universidad de Salamanca (ES)
- Universität Innsbruck (AT)
- Université Paris Cité (FR)
- Tel Aviv Sourasky Medical Center (IL)
- Great Ormond Street Hospital (GB)
- Maastricht University Medical Centre (NL)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Kinderkrankenhaus auf der Bult (DE)
- Institut Necker Enfants Malades (FR)
- MSB Medical School Berlin (DE)
- University Hospital Münster (DE)
- Hospital Infantil Universitario Niño Jesús (ES)
- Medical University of Lodz (PL)
- Bambino Gesù Children's Hospital (IT)
- Instituto de Investigación Biomédica de Salamanca (ES)
- Queen Victoria Hospital NHS Foundation Trust (GB)
- Spitalul Clinic Colentina (RO)
- Helios Hospital Berlin-Buch (DE)
- Hôpital de l'enfance (CH)
- Institut des Maladies Génétiques Imagine (FR)
- University College London (GB)
- Nagoya University (JP)
- Ludwig-Maximilians-Universität München (DE)
- University of Lausanne (CH)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1093/bjd/ljaf076
- Citations
- 5
- Primary Topic
- Skin and Cellular Biology Research
- Type
- article
- Field-Weighted Citation Impact
- 5.76