Large Pontine Cavernoma with Hemorrhage: Case Report on Surgical Approach and Recovery

<b>Background/Objectives:</b> Pontine cavernomas are rare and challenging vascular malformations, representing a critical subset of brainstem lesions due to their deep location and proximity to essential neural structures. When hemorrhagic, these lesions can cause rapid neurological deterioration, posing life-threatening risks. Management requires a delicate balance between aggressive intervention and preserving vital functions. This case report presents the successful surgical treatment of a giant hemorrhagic pontine cavernoma, highlighting the integration of advanced imaging, precision surgical techniques, and multidisciplinary care to achieve an exceptional patient outcome. <b>Methods:</b> A 47-year-old female presented with acute neurological deterioration, including severe right-sided hemiparesis, dysphagia, and obnubilation. High-resolution MRI, including susceptibility-weighted imaging, confirmed a giant hemorrhagic pontine cavernoma causing brainstem compression. An urgent left-sided pterional craniotomy with a transsylvian approach was performed to access the lesion. Subtotal resection and hematoma evacuation were carried out to relieve brainstem compression while preserving critical structures. Postoperative recovery and lesion stability were evaluated through clinical assessments and imaging after three months. <b>Results:</b> Postoperatively, the patient exhibited marked neurological recovery, with near-complete resolution of hemiparesis, restored swallowing function, and significant functional improvement. Follow-up imaging confirmed a stable residual lesion, no recurrence of hemorrhage, and a well-preserved ventricular system. The combination of early intervention and tailored surgical strategies resulted in a highly favorable outcome. <b>Conclusions:</b> This case underscores the complexity of managing giant hemorrhagic pontine cavernomas and demonstrates that carefully planned surgical intervention, combined with advanced imaging and patient-focused care, can yield remarkable outcomes. It highlights the critical importance of early diagnosis, meticulous surgical planning, and future innovations in neurovascular surgery to improve outcomes in these rare but high-stakes cases.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-03-29
DOI
https://doi.org/10.3390/jcm14072358
Citations
8
Primary Topic
Vascular Malformations Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
11.11
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article

Large Pontine Cavernoma with Hemorrhage: Case Report on Surgical Approach and Recovery

Răzvan-Adrian Covache-Busuioc, Mugurel Petrinel Rădoi, Adrian Dumitru, Daniel Ovidiu Costea et al.
8 citations
Journal of Clinical Medicine
Vascular Malformations Diagnosis and Treatment
11.11
article

Large Pontine Cavernoma with Hemorrhage: Case Report on Surgical Approach and Recovery

Răzvan-Adrian Covache-Busuioc, Mugurel Petrinel Rădoi, Adrian Dumitru, Daniel Ovidiu Costea, Matei Șerban, Alexandru Vlad Ciurea, Lucian Eva, Corneliu Toader
article en
8 citations

Abstract

<b>Background/Objectives:</b> Pontine cavernomas are rare and challenging vascular malformations, representing a critical subset of brainstem lesions due to their deep location and proximity to essential neural structures. When hemorrhagic, these lesions can cause rapid neurological deterioration, posing life-threatening risks. Management requires a delicate balance between aggressive intervention and preserving vital functions. This case report presents the successful surgical treatment of a giant hemorrhagic pontine cavernoma, highlighting the integration of advanced imaging, precision surgical techniques, and multidisciplinary care to achieve an exceptional patient outcome. <b>Methods:</b> A 47-year-old female presented with acute neurological deterioration, including severe right-sided hemiparesis, dysphagia, and obnubilation. High-resolution MRI, including susceptibility-weighted imaging, confirmed a giant hemorrhagic pontine cavernoma causing brainstem compression. An urgent left-sided pterional craniotomy with a transsylvian approach was performed to access the lesion. Subtotal resection and hematoma evacuation were carried out to relieve brainstem compression while preserving critical structures. Postoperative recovery and lesion stability were evaluated through clinical assessments and imaging after three months. <b>Results:</b> Postoperatively, the patient exhibited marked neurological recovery, with near-complete resolution of hemiparesis, restored swallowing function, and significant functional improvement. Follow-up imaging confirmed a stable residual lesion, no recurrence of hemorrhage, and a well-preserved ventricular system. The combination of early intervention and tailored surgical strategies resulted in a highly favorable outcome. <b>Conclusions:</b> This case underscores the complexity of managing giant hemorrhagic pontine cavernomas and demonstrates that carefully planned surgical intervention, combined with advanced imaging and patient-focused care, can yield remarkable outcomes. It highlights the critical importance of early diagnosis, meticulous surgical planning, and future innovations in neurovascular surgery to improve outcomes in these rare but high-stakes cases.

Journal of Clinical MedicineVol. 14(7)
Carol Davila University of Medicine and Pharmacy (RO), Clinical Emergency Hospital Bucharest (RO), Victor Babeș University of Medicine and Pharmacy Timișoara (RO), Romanian Academy (RO)
Openalex Percentile: Top 1%
Vascular Malformations Diagnosis and Treatment
11.11
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