CDKN2A Chromogenic In Situ Hybridization for Separating Benign From Malignant Mesothelial Proliferations
CDKN2A FISH is a standard method for separating mesotheliomas from reactive mesothelial proliferations, but FISH requires specialized equipment and technical expertise for interpretation. Here, we show that a commercially available CDKN2A CISH probe provides equivalent information but can be easily scored using an ordinary light microscope and does not require specialized training.
Authors
- Andrew Churg (ORCID: https://orcid.org/0000-0002-4851-8517)
- Tara Spence (ORCID: https://orcid.org/0000-0001-7098-4103)
- Stephen Yip (ORCID: https://orcid.org/0000-0002-8514-9861)
- Karina Chornenka Martin (ORCID: https://orcid.org/0009-0001-4541-1036)
- Julia Naso (ORCID: https://orcid.org/0000-0002-7799-7860)
- Janine Senz (ORCID: https://orcid.org/0009-0007-5475-4974)
Institutions
- University of British Columbia (CA)
- Vancouver General Hospital (CA)
Publication Details
- Journal
- The American Journal of Surgical Pathology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1097/pas.0000000000002395
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00