Low CD4 count was characterized in recent HIV CRF01_AE infection and it rapidly increased to reach a peak in the first year since ART initiation
CRF01_AE rapidly reduced CD4 count during the recent HIV infection. The CD4 count of the recently infected individuals with CRF01_AE increased sharply and reached its highest level of recovery within the first year of ART initiation. This study revealed an important time point for estimating CD4 count recovery post-ART in individuals with different HIV subtypes.
Authors
- Yilin Zhao (ORCID: https://orcid.org/0000-0002-7527-9056)
- Hong Ling (ORCID: https://orcid.org/0000-0002-1886-1242)
- Hongrui Zhu (ORCID: https://orcid.org/0000-0001-6823-6827)
- Wen‐Juan Wei (ORCID: https://orcid.org/0000-0003-1442-9986)
- Xianghui Wei
- Shengyu Huang (ORCID: https://orcid.org/0000-0003-0198-1405)
- Wei Liu (ORCID: https://orcid.org/0000-0001-5659-6139)
- Jiang Yue (ORCID: https://orcid.org/0000-0001-8906-1253)
- Jiaye Wang (ORCID: https://orcid.org/0009-0006-0132-2492)
- Li Wang (ORCID: https://orcid.org/0000-0002-3600-1254)
- Dan Wang (ORCID: https://orcid.org/0000-0002-8583-448X)
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-2139-3697)
- Fei Teng (ORCID: https://orcid.org/0000-0001-9076-8862)
- Xueying Zhang (ORCID: https://orcid.org/0000-0003-1269-7493)
- Jinliang Li (ORCID: https://orcid.org/0000-0002-9869-9838)
- Min Zhuang
Institutions
- Harbin Medical University (CN)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
- Heilongjiang Provincial Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s12879-025-10799-5
- Citations
- 1
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Heilongjiang Province