The prognostic significance of semi-quantitative metabolic parameters and tumoral metabolic activity based on 123I-MIBG SPECT/CT in pretreatment neuroblastoma patients
In this exploratory study, pretherapeutic <sup>123</sup>I-MIBG image-derived semi-quantitative metabolic parameters and tumor asphericity provided prognostic value for EFS in NB patients. Tmax/Lmax [Formula: see text]undefined]]>6 and ASP [Formula: see text]undefined]]>34%, along with the presence of bone/bone marrow metastasis, could be considered as supplementary factors alongside existing ones.
Authors
- Guanyun Wang (ORCID: https://orcid.org/0000-0002-7904-1504)
- Ziang Zhou (ORCID: https://orcid.org/0000-0002-1577-9489)
- Jigang Yang (ORCID: https://orcid.org/0000-0002-0538-7676)
- Kejing Ying (ORCID: https://orcid.org/0000-0001-9642-3929)
- Jun Liu (ORCID: https://orcid.org/0000-0002-7567-0055)
- Wei Wang (ORCID: https://orcid.org/0000-0002-3422-0402)
- Xiaoya Wang (ORCID: https://orcid.org/0000-0003-0519-8661)
- Xu Yang
- Yanfeng Xu (ORCID: https://orcid.org/0000-0003-0947-7254)
Institutions
- Capital Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Cancer Imaging
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s40644-025-00858-0
- Citations
- 2
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- National Natural Science Foundation of China
- Beijing Municipal Natural Science Foundation
- Beijing Nova Program