Impact of prolonged use of NSAID (Diclofenac) on 99mTc-MAG3 and 99mTc-DTPA renography

Chronic diclofenac exposure significantly delays Tmax and T½ for both tracers, with a greater impact observed using 99mTc-DTPA. These findings highlight 99mTc-MAG3 as the preferred radiopharmaceutical for renography in settings involving long-term NSAID administration, ensuring accurate and reliable interpretation and minimizing variability associated with radiopharmaceutical selection.

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Publication Details

Journal
EJNMMI Radiopharmacy and Chemistry
Published
2025-03-31
DOI
https://doi.org/10.1186/s41181-024-00325-4
Citations
2
Primary Topic
Pediatric Urology and Nephrology Studies
Type
article
Field-Weighted Citation Impact
6.99
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article

Impact of prolonged use of NSAID (Diclofenac) on 99mTc-MAG3 and 99mTc-DTPA renography

Abdelhamid H. Elgazzar, Seham Mustafa
2 citations
EJNMMI Radiopharmacy and Chemistry
Pediatric Urology and Nephrology Studies
6.99
article

Impact of prolonged use of NSAID (Diclofenac) on 99mTc-MAG3 and 99mTc-DTPA renography

Abdelhamid H. Elgazzar, Seham Mustafa
article en
2 citations

Abstract

Chronic diclofenac exposure significantly delays Tmax and T½ for both tracers, with a greater impact observed using 99mTc-DTPA. These findings highlight 99mTc-MAG3 as the preferred radiopharmaceutical for renography in settings involving long-term NSAID administration, ensuring accurate and reliable interpretation and minimizing variability associated with radiopharmaceutical selection.

EJNMMI Radiopharmacy and ChemistryVol. 10(1)
Public Authority for Applied Education and Training (KW), Kuwait University (KW)
Good health and well-being
Openalex Percentile: Top 5%
Pediatric Urology and Nephrology Studies
6.99
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