Computed tomography chest imaging for the detection of pulmonary hypertension in patients with post-tuberculosis lung disease
<b>What the study adds.</b> This study investigated the use of computed tomography (CT) chest imaging to detect pulmonary hypertension (PH) in patients with post-tuberculosis lung disease (PTLD). It revealed significant correlations between the CT-measured pulmonary artery/ascending aorta (PA/AA) diameter ratio and pulmonary artery diameter (PAD), and echocardiographic measures of PH. Notably, a low PA/AA ratio effectively rules out PH, while a high ratio warrants further investigation.<b>Implications of the findings.</b> These findings suggest that CT imaging, particularly PA/AA ratio measurements, could serve as a valuable initial screening tool for ruling out PH in patients with PTLD, particularly in settings with limited access to echocardiography. However, a high PA/AA in PTLD requires confirmation of PH by other means, owing to a low positive predictive value.
Authors
- Stephanie Griffith‐Richards (ORCID: https://orcid.org/0000-0002-7031-8108)
- Marwan Almubarek (ORCID: https://orcid.org/0000-0003-1206-7459)
- Alfonso Pecoraro (ORCID: https://orcid.org/0000-0001-6549-9402)
- Brian Allwood (ORCID: https://orcid.org/0000-0003-0421-2978)
- Christelle Ackermann (ORCID: https://orcid.org/0000-0002-4598-1127)
- Nicola Baines (ORCID: https://orcid.org/0009-0004-1165-0858)
- Elvis M. Irusen (ORCID: https://orcid.org/0000-0002-2134-3251)
- CFN Koegelenberg
- Elizabeth H. Louw (ORCID: https://orcid.org/0000-0003-4385-2249)
- Helen Thomson (ORCID: https://orcid.org/0000-0002-3259-5438)
Institutions
- Stellenbosch University (ZA)
- Tygerberg Hospital (ZA)
- Cleveland Clinic London (GB)
Publication Details
- Journal
- African Journal of Thoracic and Critical Care Medicine
- Published
- 2025-03-28
- DOI
- https://doi.org/10.7196/ajtccm.2025.v31i1.1948
- Citations
- 2
- Primary Topic
- Pericarditis and Cardiac Tamponade
- Type
- article
- Field-Weighted Citation Impact
- 2.78