Computed tomography chest imaging for the detection of pulmonary hypertension in patients with post-tuberculosis lung disease

<b>What the study adds.</b> This study investigated the use of computed tomography (CT) chest imaging to detect pulmonary hypertension (PH) in patients with post-tuberculosis lung disease (PTLD). It revealed significant correlations between the CT-measured pulmonary artery/ascending aorta (PA/AA) diameter ratio and pulmonary artery diameter (PAD), and echocardiographic measures of PH. Notably, a low PA/AA ratio effectively rules out PH, while a high ratio warrants further investigation.<b>Implications of the findings.</b> These findings suggest that CT imaging, particularly PA/AA ratio measurements, could serve as a valuable initial screening tool for ruling out PH in patients with PTLD, particularly in settings with limited access to echocardiography. However, a high PA/AA in PTLD requires confirmation of PH by other means, owing to a low positive predictive value.

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Publication Details

Journal
African Journal of Thoracic and Critical Care Medicine
Published
2025-03-28
DOI
https://doi.org/10.7196/ajtccm.2025.v31i1.1948
Citations
2
Primary Topic
Pericarditis and Cardiac Tamponade
Type
article
Field-Weighted Citation Impact
2.78
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article

Computed tomography chest imaging for the detection of pulmonary hypertension in patients with post-tuberculosis lung disease

Stephanie Griffith‐Richards, Marwan Almubarek, Alfonso Pecoraro, Brian Allwood et al.
2 citations
African Journal of Thoracic and Critical Care Medicine
Pericarditis and Cardiac Tamponade
2.78
article

Computed tomography chest imaging for the detection of pulmonary hypertension in patients with post-tuberculosis lung disease

Stephanie Griffith‐Richards, Marwan Almubarek, Alfonso Pecoraro, Brian Allwood, Christelle Ackermann, Nicola Baines, Elvis M. Irusen, CFN Koegelenberg, Elizabeth H. Louw, Helen Thomson
article en
2 citations

Abstract

<b>What the study adds.</b> This study investigated the use of computed tomography (CT) chest imaging to detect pulmonary hypertension (PH) in patients with post-tuberculosis lung disease (PTLD). It revealed significant correlations between the CT-measured pulmonary artery/ascending aorta (PA/AA) diameter ratio and pulmonary artery diameter (PAD), and echocardiographic measures of PH. Notably, a low PA/AA ratio effectively rules out PH, while a high ratio warrants further investigation.<b>Implications of the findings.</b> These findings suggest that CT imaging, particularly PA/AA ratio measurements, could serve as a valuable initial screening tool for ruling out PH in patients with PTLD, particularly in settings with limited access to echocardiography. However, a high PA/AA in PTLD requires confirmation of PH by other means, owing to a low positive predictive value.

African Journal of Thoracic and Critical Care MedicineVol. 31(1)
Stellenbosch University (ZA), Tygerberg Hospital (ZA), Cleveland Clinic London (GB)
Good health and well-being
Openalex Percentile: Top 11%
Pericarditis and Cardiac Tamponade
2.78
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Computed tomography chest imaging for the detection of pulmonary hypertension in patients with post-tuberculosis lung disease — Stephanie Griffith‐Richards, Marwan Almubarek, et al. · African Journal of Thoracic and Critical Care Medicine (2025) | TGRS Research Map | TGRS