Predictors of pathological complete response after total neoadjuvant treatment using short course radiotherapy for locally advanced rectal cancer
Mucinous component and chemotherapy interruption are associated with lower pCR rates. Integrating these factors into personalized treatment algorithms may help optimize therapeutic strategies and improve outcomes for patients with LARC.
Authors
- Amel Mézlini (ORCID: https://orcid.org/0000-0001-5995-443X)
- Haythem Yacoub (ORCID: https://orcid.org/0000-0002-0042-7704)
- N. Maàmouri
- Najla Attia (ORCID: https://orcid.org/0009-0005-5936-4049)
- Yosr Zenzri (ORCID: https://orcid.org/0000-0002-0520-8594)
- Khadija Ben Zid
- Feryel Letaief
- Dhouha Chérif
- Hajer Ben Mansour
- Cyrine Mokrani (ORCID: https://orcid.org/0009-0003-2765-8937)
Institutions
- Institut Salah-Azaïz (TN)
- Hôpital La Rabta (TN)
- Tunis El Manar University (TN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s12876-025-03709-1
- Citations
- 1
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05