Causal association between non-steroidal anti-inflammatory drugs use and the risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study
The results of the MR estimates suggest that genetically predicted NSAIDs use may elevate the risk of BPH. This outcome prompts the imperative for deeper exploration into potential underlying mechanisms.
Authors
- Jia‐Hao Dou (ORCID: https://orcid.org/0000-0001-8982-2833)
- Zihe Peng (ORCID: https://orcid.org/0000-0002-5603-6147)
- Zhaolun Li (ORCID: https://orcid.org/0000-0001-8519-5246)
- Yao Dong (ORCID: https://orcid.org/0000-0002-4425-3793)
- Tie Chong (ORCID: https://orcid.org/0000-0002-2035-6544)
- Minxin He
- Zihao Li (ORCID: https://orcid.org/0000-0002-4040-8188)
- Yawen Wang (ORCID: https://orcid.org/0009-0002-2733-7917)
- Jing Liu (ORCID: https://orcid.org/0000-0002-9728-8893)
- Mingrui Li (ORCID: https://orcid.org/0000-0003-1217-6567)
- Chia-Sheng Yan
Institutions
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s12920-025-02128-1
- Citations
- 1
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 1.84
Funders
- National Natural Science Foundation of China