Performance comparison of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus in detecting <i>Mycobacterium tuberculosis</i> infection among HIV patients in China
The diagnostic performance of QFT-GIT and QFT-Plus for <i>Mycobacterium tuberculosis</i> infection among PLHIV with relatively higher CD4 counts was found to be comparable. Additionally, our investigation revealed that irrespective of the treatment regimen, whether it involved chemotherapy or immunotherapy, preventive <i>Mycobacterium tuberculosis</i> infection interventions among PLHIV consistently led to a reduction in IFN-γ levels.
Authors
- Limei Zhu (ORCID: https://orcid.org/0000-0002-0448-8547)
- Peng Lü (ORCID: https://orcid.org/0000-0003-2703-7578)
- Fang Ge (ORCID: https://orcid.org/0000-0001-5792-5379)
- Kai Wu
- Hui Ding (ORCID: https://orcid.org/0000-0001-8108-2535)
- Qiao Liu (ORCID: https://orcid.org/0000-0002-6620-1994)
- Haitao Yang
- Xiaoyan Ding (ORCID: https://orcid.org/0009-0007-6715-6842)
- Yu Lian (ORCID: https://orcid.org/0000-0003-3688-5499)
- Wei Lu (ORCID: https://orcid.org/0000-0002-3533-6810)
- Jingjing Pan (ORCID: https://orcid.org/0000-0002-2806-2102)
Institutions
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- Southeast University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-03-31
- DOI
- https://doi.org/10.7717/peerj.19195
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Government of Jiangsu Province