The role of infection in root resorption mechanism and clinical implication

The aim of the Review is to explore the role of infection in the pathogenesis of root resorption and discuss its clinical implications and management strategies.Root resorption is a pathological condition involving the destruction of hard tissues such as dentin and cementum, often influenced by infection.The process is complex, requiring a multidisciplinary approach for effective management.A comprehensive review of the literature was conducted, focusing on infectiondriven root resorption mechanisms, diagnostic techniques, and emerging treatment modalities.Infection-driven root resorption involves microbial invasion, an inflammatory response, osteoclastic activation, and tissue destruction.Early diagnosis and effective management strategies, including antimicrobial therapy, regenerative techniques, and advanced imaging, are critical for successful outcomes.Infection plays a central role in root resorption, emphasizing the importance of timely intervention.Emerging technologies and targeted therapies offer promising advances in diagnosis and treatment, necessitating ongoing research to enhance clinical outcomes.