circACTN4 promotes breast cancer cell cycle progression and oncogenesis via c-MYC induced histone H4 acetylation
Taken together, our findings reveal for the first time a new mechanism by which circACTN4 could promote oncogenesis and the development of BC by increasing the AcH4 of MYC target genes via TIP60. Therefore, circACTN4 could be a novel target for BC diagnosis and remedy.
Authors
- K. Liu (ORCID: https://orcid.org/0000-0003-4529-3356)
- Xiaosong Wang (ORCID: https://orcid.org/0000-0002-2663-8331)
- J Chen
- Lei Xing (ORCID: https://orcid.org/0000-0003-2536-5359)
- Bowen Shi (ORCID: https://orcid.org/0000-0002-5059-9547)
- Xin Yang (ORCID: https://orcid.org/0000-0003-2019-6568)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.061721
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00