Persistent Tissue-Level Hypoperfusion (No-Reflow) Negates the Clinical Benefit of Successful Thrombectomy
When no-reflow occurred, clinical and radiological outcomes in patients with full angiographic recanalization were similar to patients with unsuccessful thrombectomy. Preventing or reversing no-reflow has the potential to augment the clinical benefit of reperfusion treatment in ischemic stroke.
Authors
- Helen M. Dewey (ORCID: https://orcid.org/0000-0001-9484-2070)
- Leonid P. Churilov (ORCID: https://orcid.org/0000-0002-9807-6606)
- Nawaf Yassi (ORCID: https://orcid.org/0000-0002-0685-0060)
- Timothy John Kleinig (ORCID: https://orcid.org/0000-0003-4430-3276)
- Samantha Rivet (ORCID: https://orcid.org/0000-0001-6099-237X)
- Geoffrey Alan Donnan (ORCID: https://orcid.org/0000-0001-6324-3403)
- Patricia Desmond (ORCID: https://orcid.org/0000-0002-4803-6323)
- Stephen M. Davis (ORCID: https://orcid.org/0000-0003-0962-2300)
- Vincent Thijs (ORCID: https://orcid.org/0000-0002-6614-8417)
- Felix Ng (ORCID: https://orcid.org/0000-0001-6973-8677)
- Peter Mitchell (ORCID: https://orcid.org/0000-0002-8337-7529)
- Bruce C.V. Campbell (ORCID: https://orcid.org/0000-0003-3632-9433)
- Mark William Parsons (ORCID: https://orcid.org/0000-0001-8874-2487)
- Teddy Y. Wu (ORCID: https://orcid.org/0000-0003-1845-1769)
Institutions
- Royal Adelaide Hospital (AU)
- The Royal Melbourne Hospital (AU)
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- Austin Hospital (AU)
- Christchurch Hospital (NZ)
- UNSW Sydney (AU)
- Eastern Health (AU)
- University of Otago (NZ)
Publication Details
- Journal
- Stroke
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1161/strokeaha.124.049574
- Citations
- 14
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 18.96