A novel approach for the co-delivery of 5-fluorouracil and everolimus for breast cancer combination therapy: stimuli-responsive chitosan hydrogel embedded with mesoporous silica nanoparticles
These findings underscore the potential of the nanocomposite used to develop a novel co-delivery system to enhance therapeutic outcomes, reduce side effects, and provide a promising new strategy for future cancer treatments.
Authors
- Akram Alizadeh (ORCID: https://orcid.org/0000-0002-9956-4556)
- Ebrahim Soleiman Dehkordi (ORCID: https://orcid.org/0000-0003-2120-2747)
- Fatemeh Deris (ORCID: https://orcid.org/0000-0002-7929-9230)
- Elham Bijad (ORCID: https://orcid.org/0000-0002-4210-8912)
- Seyed Abbas Mirzaei (ORCID: https://orcid.org/0000-0003-0307-3750)
- Pooria Mohammadi Arvejeh (ORCID: https://orcid.org/0000-0001-9829-9941)
- Francesco M. Marincola (ORCID: https://orcid.org/0000-0001-6423-391X)
- Pegah Khosravian (ORCID: https://orcid.org/0000-0002-4802-8534)
- Fatemeh Amini Chermahini
- Rahim Jafari (ORCID: https://orcid.org/0000-0003-0931-835X)
- Fatemeh Taheri (ORCID: https://orcid.org/0000-0002-7267-9089)
- Neda Amiri (ORCID: https://orcid.org/0000-0003-2185-3347)
- Amin Soltani (ORCID: https://orcid.org/0000-0002-4856-4855)
Institutions
- Shahrekord University of Medical Sciences (IR)
- Semnan University of Medical Sciences (IR)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s12967-025-06396-4
- Citations
- 12
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 7.17
Funders
- Shahrekord University of Medical Sciences