Antibacterial effect of polylactic-co-glycolic acid/selenium nanocomposite against dental biofilm
To determine the optimal conditions for obtaining poly(lactic-co-glycolic) acid with selenium (PLGA/selenium) nanocomposites the Taguchi method was used. FT-IR, Raman spectroscopy, XRD and FESEM analysis confirmed the nanocomposites’ structure. The nanocomposite containing 6 mg/mL of selenium obtained in the process where the mixing time was 75 min showed the highest antibacterial activity against Streptococcus mutans. The obtained nanocomposites are an innovative approach to improving oral health and can be used as antibacterial materials for medical and dental applications.
Authors
- Sharareh Ahmadi
- Ling Shing Wong (ORCID: https://orcid.org/0000-0002-5869-0804)
- Douglas Law (ORCID: https://orcid.org/0000-0002-7824-3542)
- Mohammad Salmani Mobarakeh (ORCID: https://orcid.org/0000-0002-3272-4041)
- Mohsen Safaei (ORCID: https://orcid.org/0000-0003-3885-6640)
- T.A. Nhlapo (ORCID: https://orcid.org/0000-0001-5670-4056)
- D. Ravinder (ORCID: https://orcid.org/0000-0002-0626-3034)
- Mohammad Hashim (ORCID: https://orcid.org/0000-0003-0231-0697)
- Azra Parveen (ORCID: https://orcid.org/0000-0003-2444-3503)
- Farnoosh Khaleseh
Institutions
- INTI International University (MY)
- Aligarh Muslim University (IN)
- Sefako Makgatho Health Sciences University (ZA)
- Kermanshah University of Medical Sciences (IR)
- Osmania University (IN)
Publication Details
- Journal
- Polimery
- Published
- 2025-03-27
- DOI
- https://doi.org/10.14314/polimery.2025.3.4
- Citations
- 1
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39