Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits

We utilized bioinformatics to screen 184 genes potentially associated with litter size in New Zealand female rabbits. Among these, CXCL12 plays a role in regulating the expression of cell cycle-related genes, promoting GCs proliferation. As a result, CXCL12 emerges as a promising candidate marker for selecting high litter size female rabbits in future breeding and production practices.

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Publication Details

Journal
Animal Bioscience
Published
2025-03-31
DOI
https://doi.org/10.5713/ab.24.0640
Primary Topic
Rabbits: Nutrition, Reproduction, Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits

Zhiyuan Bao, Jiawei Cai, Bohao Zhao, Pin Zhai et al.
Animal Bioscience
Rabbits: Nutrition, Reproduction, Health
article

Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits

Zhiyuan Bao, Jiawei Cai, Bohao Zhao, Pin Zhai, Xinsheng Wu, Ping Zhao, Chen Yang, Jiali Li, Jie Yang
article en

Abstract

We utilized bioinformatics to screen 184 genes potentially associated with litter size in New Zealand female rabbits. Among these, CXCL12 plays a role in regulating the expression of cell cycle-related genes, promoting GCs proliferation. As a result, CXCL12 emerges as a promising candidate marker for selecting high litter size female rabbits in future breeding and production practices.

Animal BioscienceVol. 39(1)
Jiangsu Academy of Agricultural Sciences (CN), Yangzhou University (CN)
Zero hunger
Openalex Percentile: Top 94%
Rabbits: Nutrition, Reproduction, Health
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