Microsatellite Instability as a Risk Factor for Occult Lymph Node Metastasis in Early-Stage Endometrial Cancer: A Retrospective Multicenter Study
MSI is independently associated with a higher risk of occult LNMs in early-stage EC, suggesting a potential role for MSI profiling in refining lymph node staging strategies. Future prospective studies should assess the prognostic impact of this association and its implications for surgical decision-making.
Authors
- Stefano Restaino (ORCID: https://orcid.org/0000-0002-7848-0329)
- Vito Chiàntera (ORCID: https://orcid.org/0000-0002-6294-3720)
- Giuseppe Cucinella (ORCID: https://orcid.org/0000-0001-8574-7346)
- Giuseppe Vizzielli (ORCID: https://orcid.org/0000-0002-2424-2691)
- Carlo Ronsini (ORCID: https://orcid.org/0000-0002-9023-282X)
- Mariano Catello Di Donna (ORCID: https://orcid.org/0000-0002-8830-1865)
- Antonio Raffone (ORCID: https://orcid.org/0000-0001-5443-2333)
- Federico Paparcura (ORCID: https://orcid.org/0009-0007-0881-7233)
- Pasquale De Franciscis
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Cancers
- Published
- 2025-03-30
- DOI
- https://doi.org/10.3390/cancers17071162
- Citations
- 5
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 10.29