Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza A Virus
These findings suggest that the combined use of black elderberry extract and quinine might serve as an effective antiviral strategy against IAV and SARS-CoV-2, particularly since the synergistic effect allows for lower doses of each product while retaining therapeutic efficacy. In summary, this combinational in vitro approach, when expanded to other respiratory RNA viruses and confirmed in clinical studies, has the potential to open a promising avenue for pandemic preparedness.
Authors
- Christian Setz
- Stephan Plattner (ORCID: https://orcid.org/0000-0003-1025-0284)
- Pia Rauch
- Ulrich S. Schubert (ORCID: https://orcid.org/0000-0003-4978-4670)
- Melanie Setz
- Stephan Breitenberger
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
Publication Details
- Journal
- Nutrients
- Published
- 2025-03-29
- DOI
- https://doi.org/10.3390/nu17071205
- Citations
- 5
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 6.98
Funders
- Deutsche Forschungsgemeinschaft