Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza A Virus

These findings suggest that the combined use of black elderberry extract and quinine might serve as an effective antiviral strategy against IAV and SARS-CoV-2, particularly since the synergistic effect allows for lower doses of each product while retaining therapeutic efficacy. In summary, this combinational in vitro approach, when expanded to other respiratory RNA viruses and confirmed in clinical studies, has the potential to open a promising avenue for pandemic preparedness.

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Publication Details

Journal
Nutrients
Published
2025-03-29
DOI
https://doi.org/10.3390/nu17071205
Citations
5
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
6.98

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article

Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza A Virus

Christian Setz, Stephan Plattner, Pia Rauch, Ulrich S. Schubert et al.
5 citations
Nutrients
SARS-CoV-2 and COVID-19 Research
6.98
article

Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza A Virus

Christian Setz, Stephan Plattner, Pia Rauch, Ulrich S. Schubert, Melanie Setz, Stephan Breitenberger
article en
5 citations

Abstract

These findings suggest that the combined use of black elderberry extract and quinine might serve as an effective antiviral strategy against IAV and SARS-CoV-2, particularly since the synergistic effect allows for lower doses of each product while retaining therapeutic efficacy. In summary, this combinational in vitro approach, when expanded to other respiratory RNA viruses and confirmed in clinical studies, has the potential to open a promising avenue for pandemic preparedness.

NutrientsVol. 17(7)
Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
Deutsche Forschungsgemeinschaft
Openalex Percentile: Top 3%
SARS-CoV-2 and COVID-19 Research
6.98
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