Study on the types and status of alternative animal testing for cosmetics evaluation

Testing methods that replace animals for experiments are essential. In the future, alternative testing methods should be able to increase the accuracy and efficiency of experimental results along with ethical directions. In addition, in most cases, it can save costs and time compared to testing using animals. Recently, cell culture, artificial skin, QSAR, and omics data-based analysis have been attracting attention as alternative testing methods for animals. In particular, toxicity and efficacy studies based on big data are being conducted in combination with AI. Among them, the zebrafish model is very useful for research on toxicity and aging, and is suitable for in vivo studies as an alternative animal model. Zebrafish is also expected to converge with bioprinting, AI, and big data.