Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China
This is the first study in which complete genomic characterization of the rare NDM-1-producing ST592 <i>K. pneumoniae</i> clinical isolate was performed. This study provides a possible evolutionary hypothesis for the formation of CR-hvKp via conjugation. Early detection is recommended to avoid the extensive spread of this clone.
Authors
- Su Dong
- Huan Zhang (ORCID: https://orcid.org/0000-0001-8625-8050)
- Caiping Mao (ORCID: https://orcid.org/0000-0003-0418-1075)
- Junjie Ying
- Yong Fang (ORCID: https://orcid.org/0000-0002-0588-2116)
Institutions
- Zhejiang Chinese Medical University (CN)
- Chinese Academy of Sciences (CN)
- Wenzhou Medical University (CN)
- Zhejiang Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.3389/fcimb.2025.1565980
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shaoxing Bureau of Science and Technology