Influence of dendritic cells on corneal nerve morphological analysis and clinical relevance in chronic dry eye disease after femtosecond laser-assisted laser in situ keratomileusis
The presence of DCs introduces significant biases in the assessments of corneal nerve morphology, primarily false-positive results in DED especially chronic FS-LASIK related DED. Their exclusion improves the precision of nerve measurements, which may enhance the clinical evaluation of corneal nerve morphology. These findings highlight the importance of precise segmentation techniques to minimize DCs related interference in clinical practice.
Authors
- Hong Qi
- Zhao Lu (ORCID: https://orcid.org/0000-0003-1298-8936)
- Yitian Zhao (ORCID: https://orcid.org/0000-0003-4357-4592)
- Baikai Ma
- Yilin Liu (ORCID: https://orcid.org/0000-0002-8491-914X)
- Zhengze Sun (ORCID: https://orcid.org/0000-0003-3896-5353)
- Heng Li (ORCID: https://orcid.org/0000-0002-1303-8898)
- Wenlong Li
- Hongyu Duan (ORCID: https://orcid.org/0000-0003-2961-7082)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Chinese Academy of Sciences (CN)
- Peking University (CN)
- Peking University Third Hospital (CN)
- Ningbo Institute of Industrial Technology (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-03-31
- DOI
- https://doi.org/10.3389/fmed.2025.1568787
- Citations
- 1
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 1.88