GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism
Targeting metabolic pathways using the GLP-1R/GCGR dual agonist TB001 shows potential for managing kidney allograft fibrosis.
Authors
- Linjie Peng (ORCID: https://orcid.org/0000-0003-1400-4611)
- Qihao Li (ORCID: https://orcid.org/0000-0002-1124-1999)
- Shuangjin Yu
- Guodong Chen (ORCID: https://orcid.org/0000-0001-7671-6281)
- Xiaobing Jiang (ORCID: https://orcid.org/0000-0001-5901-4261)
- Weijie Lai
Institutions
- Sun Yat-sen University (CN)
- Key Laboratory of Guangdong Province (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.3389/fimmu.2025.1551136
- Citations
- 8
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 15.88
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province