Longitudinal associations between pain and cognitive decline in middle-aged and older Chinese adults: the mediating role of depressive symptoms
Our study establishes a significant longitudinal link between Number of Pain Sites and cognitive decline, mediated in part by depressive symptoms. This finding underscores the need for interventions that address pain and depression to potentially decelerate cognitive decline in older adults.
Authors
- Jiayang Liu (ORCID: https://orcid.org/0000-0003-1878-8425)
- Quan Yuan (ORCID: https://orcid.org/0000-0002-2836-1081)
- Duanping Liao (ORCID: https://orcid.org/0000-0001-7405-6152)
- Jie Hu (ORCID: https://orcid.org/0000-0003-1681-815X)
- Lin Lin (ORCID: https://orcid.org/0000-0001-6246-8803)
- Kun Zhang (ORCID: https://orcid.org/0000-0002-5280-4479)
- Xian Wu Cheng (ORCID: https://orcid.org/0000-0002-9758-0632)
- Hongxia Hu
- Hang Cai
Institutions
- Chengdu Medical College (CN)
- First Affiliated Hospital of Chengdu Medical College (CN)
- Science and Technology Department of Sichuan Province (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-03-31
- DOI
- https://doi.org/10.3389/fpubh.2025.1526086
- Citations
- 4
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 8.76