Comparison of ciprofloxacin and aminoglycoside susceptibility testing for ceftriaxone non-susceptible Enterobacterales by disk diffusion and VITEK 2 vs. broth microdilution using updated Clinical and Laboratory Standards Institute breakpoints
Our findings suggest that both disk diffusion and to a greater extent the AST-N391 card for the VITEK 2 system will overcall non-susceptibility according to current CLSI breakpoints for ciprofloxacin. By contrast, the existing AST-N391 VITEK 2 card can likely be used to correctly infer susceptibility to gentamicin and tobramycin.
Authors
- Anthony Lieu (ORCID: https://orcid.org/0000-0002-5592-7001)
- Matthew P. Cheng (ORCID: https://orcid.org/0000-0002-4867-2063)
- Todd C. Lee (ORCID: https://orcid.org/0000-0002-2267-4239)
- Alexander Lawandi (ORCID: https://orcid.org/0000-0001-7948-3161)
- Zahra Sohani (ORCID: https://orcid.org/0000-0002-0770-4962)
- M.H. Patel (ORCID: https://orcid.org/0009-0006-9477-8906)
- Makeda Semret (ORCID: https://orcid.org/0000-0003-3875-4847)
- Reggie Bamba
- Nancy Simic
Institutions
- McGill University Health Centre (CA)
- Jewish General Hospital (CA)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s12866-025-03923-7
- Citations
- 2
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 2.79