Direct oral  anticoagulants versus warfarin in the treatment of cerebral venous thrombosis in bach mai hospital

Cerebral venous thrombosis (CVT) is a rare type of stroke that carries a risk of recurrence, including conditions such as limb venous thrombosis and pulmonary thrombosis… A cross-sectional study conducted at Bach Mai Hospital from January 2022 to June 2024 evaluated the safety and efficacy of oral anticoagulants, including direct oral anticoagulants (DOAC) and warfarin, in 47 patients diagnosed with cerebral venous thrombosis. The study found that the average age of the participants was 44.7 ± 16.8 years. The complete recanalization rates for the groups using DOAC and warfarin were 80.5% and 66.7%, respectively. Additionally, the proportion of patients achieving a favorable recovery, indicated by an mRS score of 0-1, was 80.5% for the DOAC group and 83.3% for the warfarin group. Importantly, the rates of recurrent venous thrombosis and bleeding events were low, at 2.4% and 4.9%, respectively. This study provides valuable information regarding the efficacy and safety of both DOAC and warfarin for patients with CVT, aiding clinicians in making informed decisions about anticoagulant therapy.

Authors

Publication Details

Journal
Tạp chí thần kinh học Việt Nam
Published
2025-03-31
DOI
https://doi.org/10.62511/vjn.44.2025.052
Primary Topic
Cerebral Venous Sinus Thrombosis
Type
article
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article

Direct oral  anticoagulants versus warfarin in the treatment of cerebral venous thrombosis in bach mai hospital

Hong Thai Vu, Hồng Khôi Võ
Tạp chí thần kinh học Việt Nam
Cerebral Venous Sinus Thrombosis
article

Direct oral  anticoagulants versus warfarin in the treatment of cerebral venous thrombosis in bach mai hospital

Hong Thai Vu, Hồng Khôi Võ
article en

Abstract

Cerebral venous thrombosis (CVT) is a rare type of stroke that carries a risk of recurrence, including conditions such as limb venous thrombosis and pulmonary thrombosis… A cross-sectional study conducted at Bach Mai Hospital from January 2022 to June 2024 evaluated the safety and efficacy of oral anticoagulants, including direct oral anticoagulants (DOAC) and warfarin, in 47 patients diagnosed with cerebral venous thrombosis. The study found that the average age of the participants was 44.7 ± 16.8 years. The complete recanalization rates for the groups using DOAC and warfarin were 80.5% and 66.7%, respectively. Additionally, the proportion of patients achieving a favorable recovery, indicated by an mRS score of 0-1, was 80.5% for the DOAC group and 83.3% for the warfarin group. Importantly, the rates of recurrent venous thrombosis and bleeding events were low, at 2.4% and 4.9%, respectively. This study provides valuable information regarding the efficacy and safety of both DOAC and warfarin for patients with CVT, aiding clinicians in making informed decisions about anticoagulant therapy.

Tạp chí thần kinh học Việt Nam(44)
Openalex Percentile: Top 90%
Cerebral Venous Sinus Thrombosis
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Direct oral  anticoagulants versus warfarin in the treatment of cerebral venous thrombosis in bach mai hospital — Hong Thai Vu, Hồng Khôi Võ · Tạp chí thần kinh học Việt Nam (2025) | TGRS Research Map | TGRS