Smoking and presence of human papillomavirus correlates with lymphocyte density in the stroma of penile squamous cell carcinoma

Smoking and presence of hrHPV is associated with a lower density of infiltrating lymphocytes in the stroma of PSCC. There is a positive correlation in the number of CD3<sup>+</sup> and CD8<sup>+</sup> cells between the stroma and intra-tumoral compartment of PSCC.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-03-31
DOI
https://doi.org/10.3389/fonc.2025.1568764
Primary Topic
Genital Health and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Smoking and presence of human papillomavirus correlates with lymphocyte density in the stroma of penile squamous cell carcinoma

Owen Ngalamika, Chibamba Mumba, Victor Mapulanga, Nicholas K Mwale
Frontiers in Oncology
Genital Health and Disease
article

Smoking and presence of human papillomavirus correlates with lymphocyte density in the stroma of penile squamous cell carcinoma

Owen Ngalamika, Chibamba Mumba, Victor Mapulanga, Nicholas K Mwale
article en

Abstract

Smoking and presence of hrHPV is associated with a lower density of infiltrating lymphocytes in the stroma of PSCC. There is a positive correlation in the number of CD3<sup>+</sup> and CD8<sup>+</sup> cells between the stroma and intra-tumoral compartment of PSCC.

Frontiers in OncologyVol. 15
University of Zambia (ZM)
Openalex Percentile: Top 89%
Genital Health and Disease
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