Perioperative Hemostasis Management During Open Mitral Valve Replacement in a Patient With Hypoprothrombinemia Secondary to Lupus Anticoagulant

Hypoprothrombinemia is a rare coagulopathy that complicates surgical interventions and is an uncommon manifestation of lupus anticoagulant. Perioperative coagulopathy is a major challenge in cardiac surgery. To our knowledge, the management of cardiac surgery in patients with hypoprothrombinemia has not been described in prior literature. This case report outlines the challenging surgical intervention of mitral valve replacement in a 47-year-old female patient with rheumatic valve disease (RHD) and a rare prothrombin deficiency secondary to lupus anticoagulant. This report details the multidisciplinary perioperative hemostasis management and outcomes.