Histopathologic evaluation of skin wound healing due to local application of transdermal chitosan patch in combination with doxycycline, zinc nanoparticles, and selenium nanoparticles in mice
The chitosan skin patch containing doxycycline, zinc nanoparticles, and selenium nanoparticles (CsDZnS group) demonstrated the most effective results in skin healing, as evidenced by the highest control of inflammation on days 7 and 14, the greatest re-epithelialization on day 14, and the smallest wound area on both days compared to the other evaluated groups.
Authors
- Negin Motamedi
- Elham Moghtadaei Khorasgani
- Moosa Javdani (ORCID: https://orcid.org/0000-0003-0975-2295)
- Pegah Khosravian
Institutions
- Shahrekord University (IR)
- Shahrekord University of Medical Sciences (IR)
- Islamic Azad University of Shahrekord (IR)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1186/s12917-025-04672-5
- Citations
- 4
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.10