Global Effect of Cardiovascular Risk Factors on Lifetime Estimates
The absence of five classic risk factors at 50 years of age was associated with more than a decade greater life expectancy than the presence of all five risk factors, in both sexes. Persons who modified hypertension and smoking in midlife had the most additional life-years free of cardiovascular disease and death from any cause, respectively. (Funded by the German Center for Cardiovascular Research [DZHK]; ClinicalTrials.gov number, NCT05466825.).
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- German Centre for Cardiovascular Research (DE)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-03-30
- DOI
- https://doi.org/10.1056/nejmoa2415879
- Citations
- 83
- Primary Topic
- Cardiovascular Health and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 115.22
Funders
- U.S. Department of Veterans Affairs
- Cancer Research Institute
- Emory University
- Hamilton Health Sciences
- Uniwersytet Jagielloński Collegium Medicum
- Universiti Brunei Darussalam
- Norges Teknisk-Naturvitenskapelige Universitet
- London School of Hygiene and Tropical Medicine
- McMaster University
- Deutsches Zentrum für Herz-Kreislaufforschung
- College of Pharmacy, University of Georgia
- European Commission
- South African Medical Research Council
- Public Health Foundation of India
- University of New South Wales
- Chonnam National University
- Seoul National University
- Università degli Studi di Milano-Bicocca
- Siberian Branch, Russian Academy of Sciences
- Lunds Universitet
- Universidad Nacional de La Plata
- Johannes Gutenberg-Universität Mainz
- Qatar University
- Tel Aviv University
- Tehran University of Medical Sciences and Health Services
- Mashhad University of Medical Sciences
- B.P. Koirala Institute of Health Sciences
- Instituto Tecnológico y de Estudios Superiores de Monterrey
- North-West University
- Universitetet i Oslo
- Technische Universität München
- Ludwig-Maximilians-Universität München
- Shahid Beheshti University of Medical Sciences
- Uppsala Universitet
- Tartu Ülikool
- Universität Ulm
- Faculty of Health and Medical Sciences, University of Western Australia
- Harokopio University
- Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu
- Akershus Universitetssykehus
- Baker Heart and Diabetes Institute
- Instituto Nacional De Salud Pública
- Bispebjerg Hospital
- Cardio-Pulmonary Institute
- School of Medicine, Emory University
- College of Medicine, Seoul National University
- Medical Research Council
- Cancer Council Victoria
- Russian Academy of Sciences
- Det Sundhedsvidenskabelige Fakultet, Københavns Universitet
- Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
- Horizon 2020
- Erasmus Universitair Medisch Centrum Rotterdam
- Helmholtz Zentrum München