Diagnosis of Prosthetic Joint Infection of Hips and Knees—One Size Does Not Fit All

There is no consensus on diagnostic criteria for hip and knee periprosthetic joint infections (PJIs). This study evaluated Infectious Diseases Society of America (IDSA), International Consensus Meeting 2018 (ICM2018), and European Bone and Joint Society (EBJIS) criteria, finding IDSA most accurate for early PJI and knee infections, while ICM2018 and EBJIS were superior for delayed and late cases. Diagnostic approaches should consider infection timing and context.