Dentate line invasion is a risk factor for locoregional recurrence and distant metastasis following abdominoperineal resection in rectal cancer: a single-centre retrospective cohort study based on 1854 cases
DLI correlates with a heightened likelihood of locoregional recurrence and distant metastasis among rectal cancer patients treated with APR. This association underscores the significance of DLI as a crucial prognostic factor that should be considered when developing clinical management strategies.
Authors
- Jianjun Bi (ORCID: https://orcid.org/0009-0003-1832-3430)
- Mingguang Zhang (ORCID: https://orcid.org/0000-0003-3654-0079)
- Yujuan Jiang
- Zhixun Zhao (ORCID: https://orcid.org/0000-0002-6388-3838)
- Zixing Zhu
- Haitao Zhou (ORCID: https://orcid.org/0000-0001-5325-5275)
- Wei Pei (ORCID: https://orcid.org/0000-0001-5201-6432)
- Jianwei Liang (ORCID: https://orcid.org/0000-0003-2567-5429)
- Qian Liu (ORCID: https://orcid.org/0000-0003-2510-3113)
- Qiang Feng (ORCID: https://orcid.org/0000-0002-8814-6594)
- Zheng Wang (ORCID: https://orcid.org/0000-0003-1515-2288)
- Zhaoxu Zheng
- Jichuan Quan
- Dedi Jiang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-30
- DOI
- https://doi.org/10.1186/s12885-025-14001-6
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00