Long-Term Regenerative Potential of Submandibular Glands in Albino Rats Following Radiotherapy: Role of Cytokeratin 17 Redistribution

CK17 expression differed significantly between the control and the second group, which underwent a one-month wait after the final radiation dose. In contrast, the third group, which underwent a one-year wait, showed intermediate results between the two groups, indicating a more advanced stage of recovery. Statistical analysis showed differing recovery dynamics, with ductal cells exhibiting slower recovery than acinar cells, which appeared more advanced in their healing. These findings highlight the progressive yet varied repair processes within the irradiated glands.