Serum Concentrations of IL-18, IL-21, IL-22, IL-23, IL-27, and IL-31 in Patients With Stevens-Johnson Syndrome/Toxix Epidermal Necrolysis and Their Correlation With Disease Severity
Serum levels of IL-18 were increased in TEN group. Additionally, serum concentrations of IL-18, IL-27, and IL-31 were associated with disease severity as indicated by the lesional area. These interleukins may play an important role in the pathogenesis of SJS/TEN.
Authors
- Nguyen Thi Ha Vinh (ORCID: https://orcid.org/0000-0001-6066-363X)
- Le Huu Doanh (ORCID: https://orcid.org/0000-0002-9982-9905)
- Trần Thị Huyền (ORCID: https://orcid.org/0000-0002-9794-5718)
- Phạm Thị Lan (ORCID: https://orcid.org/0000-0003-3982-1896)
- Nguyen Hoang Phuc
- Son Dao Anh (ORCID: https://orcid.org/0009-0003-4762-9674)
- Le Huyen My
Institutions
- Hanoi Medical University (VN)
- Health Strategy and Policy Institute (VN)
- Vietnam National Children's Hospital (VN)
Publication Details
- Journal
- Medical Archives
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5455/medarh.2025.79.9-14
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00