Psychotropic‐induced weight gain and telomere length

Research suggests that shortening of telomeres, protective cap‐like structures at the ends of chromosomes, as well as inflammation, are associated with decreased cellular lifespan, and as such have been implicated in several age‐related medical conditions (Gavia‐García et al., 2021). A meta‐analysis has reported an association between shorter telomere length and several psychiatric conditions, including anxiety, bipolar disorder, depression, post‐traumatic stress disorder, and psychosis (Darrow et al., 2016).

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Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2025-03-27
DOI
https://doi.org/10.1002/pu.31299
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
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article

Psychotropic‐induced weight gain and telomere length

Y. W. Francis Lam
The Brown University Psychopharmacology Update
Telomeres, Telomerase, and Senescence
article

Psychotropic‐induced weight gain and telomere length

Y. W. Francis Lam
article en

Abstract

Research suggests that shortening of telomeres, protective cap‐like structures at the ends of chromosomes, as well as inflammation, are associated with decreased cellular lifespan, and as such have been implicated in several age‐related medical conditions (Gavia‐García et al., 2021). A meta‐analysis has reported an association between shorter telomere length and several psychiatric conditions, including anxiety, bipolar disorder, depression, post‐traumatic stress disorder, and psychosis (Darrow et al., 2016).

The Brown University Psychopharmacology UpdateVol. 36(5)
Openalex Percentile: Top 92%
Telomeres, Telomerase, and Senescence
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Psychotropic‐induced weight gain and telomere length — Y. W. Francis Lam · The Brown University Psychopharmacology Update (2025) | TGRS Research Map | TGRS