Relative dose intensity of gemcitabine-nab-paclitaxel combination as second-line or more in locally advanced or metastatic pancreatic adenocarcinoma

Our results suggest that the level of GNP exposure, at a predefined RDI threshold of 70 %, had no significant effect on survival in our patients treated in L2+ for a/mPA. Alternative GNP regimens may be evaluated in patients undergoing L2+ treatment for a/mPA.

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Publication Details

Journal
Clinics and Research in Hepatology and Gastroenterology
Published
2025-03-30
DOI
https://doi.org/10.1016/j.clinre.2025.102583
Citations
2
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
2.09
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article

Relative dose intensity of gemcitabine-nab-paclitaxel combination as second-line or more in locally advanced or metastatic pancreatic adenocarcinoma

Marie Dutherage, André Gillibert, Lilian Schwarz, Adrien Grancher et al.
2 citations
Clinics and Research in Hepatology and Gastroenterology
Pancreatic and Hepatic Oncology Research
2.09
article

Relative dose intensity of gemcitabine-nab-paclitaxel combination as second-line or more in locally advanced or metastatic pancreatic adenocarcinoma

Marie Dutherage, André Gillibert, Lilian Schwarz, Adrien Grancher, Michel Pierre, Frédéric Di Fiore, David Sefrioui, Virginie Vernon, Leila Tagemouati
article en
2 citations

Abstract

Our results suggest that the level of GNP exposure, at a predefined RDI threshold of 70 %, had no significant effect on survival in our patients treated in L2+ for a/mPA. Alternative GNP regimens may be evaluated in patients undergoing L2+ treatment for a/mPA.

Clinics and Research in Hepatology and GastroenterologyVol. 49(5)
Centre Hospitalier Universitaire de Rouen (FR), Université de Rouen Normandie (FR)
Zero hunger
Openalex Percentile: Top 13%
Pancreatic and Hepatic Oncology Research
2.09
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