Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation
Among participants undergoing TAVI, routine use of CEP did not decrease the incidence of stroke within 72 hours. (Funded by the British Heart Foundation and Boston Scientific; BHF PROTECT-TAVI ISRCTN Registry number, ISRCTN16665769.).
Authors
- Saqib Chowdhary (ORCID: https://orcid.org/0000-0002-7196-0581)
- Simon Redwood (ORCID: https://orcid.org/0000-0002-1937-063X)
- Zahra Jamal (ORCID: https://orcid.org/0000-0002-3817-6795)
- Nicholas Cruden
- Raj Chelliah
- Clare Appleby (ORCID: https://orcid.org/0000-0002-3838-1174)
- Ayush Khurana (ORCID: https://orcid.org/0000-0002-2673-9319)
- James Cotton (ORCID: https://orcid.org/0000-0001-6548-2723)
- Karim Ratib (ORCID: https://orcid.org/0000-0002-4860-8213)
- James Kennedy (ORCID: https://orcid.org/0000-0002-9083-672X)
- Rod Stables (ORCID: https://orcid.org/0000-0002-9244-7015)
- Stephen Palmer (ORCID: https://orcid.org/0000-0002-0108-6999)
- Nick Curzen (ORCID: https://orcid.org/0000-0001-9651-7829)
- Richard Varcoe
- Tim Clayton (ORCID: https://orcid.org/0000-0002-1266-3288)
- Javaid Iqbal (ORCID: https://orcid.org/0000-0001-6349-8887)
- Jonathan Byrne (ORCID: https://orcid.org/0009-0003-2386-1743)
- Andreas Baumbach (ORCID: https://orcid.org/0000-0001-7707-2254)
- Ciprian Dospinescu
- Douglas Muir (ORCID: https://orcid.org/0000-0003-1871-2869)
- Robert Henderson (ORCID: https://orcid.org/0000-0002-0319-3691)
- Iqbal Malik (ORCID: https://orcid.org/0000-0002-0883-5614)
- Bernard Prendergast (ORCID: https://orcid.org/0000-0002-6031-2124)
- Rajesh Kharbanda (ORCID: https://orcid.org/0000-0002-5356-2395)
- David Hildick‐Smith (ORCID: https://orcid.org/0000-0002-1147-1436)
- Peter Ludman (ORCID: https://orcid.org/0000-0002-7237-0946)
- Andrew Wiper (ORCID: https://orcid.org/0000-0001-5401-4588)
- Adrian Banning (ORCID: https://orcid.org/0000-0002-2842-7861)
- Kiran Bal (ORCID: https://orcid.org/0000-0003-0242-8660)
- Daniel J. Blackman (ORCID: https://orcid.org/0000-0001-9039-6130)
- Alexander Perkins (ORCID: https://orcid.org/0000-0002-9817-2390)
- Charis Costopoulos (ORCID: https://orcid.org/0000-0003-0583-8876)
- Thirumaran Rajathurai
- Rajesh Aggarwal (ORCID: https://orcid.org/0000-0001-9424-9621)
- Richard Evans (ORCID: https://orcid.org/0000-0003-4101-2131)
- Richard Anderson (ORCID: https://orcid.org/0000-0001-6969-0132)
- Stephen Dorman (ORCID: https://orcid.org/0000-0003-3264-521X)
- Stuart Watkins
- Sam Firoozi
- Colum Owens
- Sagar N. Doshi (ORCID: https://orcid.org/0009-0007-5230-6254)
- Venkatesan Suresh
- Rajiv Das
- Matthew C. Dodd
- Muhiddin Ozkor
Institutions
- University of Wolverhampton (GB)
- University of London (GB)
- Swansea Bay University Health Board (GB)
- University of Leeds (GB)
- St Thomas' Hospital (GB)
- Nottingham University Hospitals NHS Trust (GB)
- University of Ulster (GB)
- University of Liverpool (GB)
- Imperial College Healthcare NHS Trust (GB)
- Queen Mary University of London (GB)
- Barts Health NHS Trust (GB)
- Leeds Teaching Hospitals NHS Trust (GB)
- New Cross Hospital (GB)
- Royal Papworth Hospital (GB)
- Royal Stoke University Hospital (GB)
- Aberdeen Royal Infirmary (GB)
- University Hospital of Wales (GB)
- Blackpool Victoria Hospital (GB)
- James Cook University Hospital (GB)
- St George’s University Hospitals NHS Foundation Trust (GB)
- Castle Hill Hospital (GB)
- University Hospital Coventry (GB)
- Hammersmith Hospital (GB)
- Freeman Hospital (GB)
- Glenfield Hospital (GB)
- University Hospitals of Leicester NHS Trust (GB)
- John Radcliffe Hospital (GB)
- Edinburgh Royal Infirmary (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- University College Birmingham (GB)
- University of Warwick (GB)
- University of Oxford (GB)
- University Foundation (BE)
- Liverpool Heart and Chest Hospital (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- King's College Hospital NHS Foundation Trust (GB)
- Essex Cardiothoracic Centre (GB)
- Royal Victoria Hospital (GB)
- NIHR Bristol Cardiovascular Biomedical Research Unit (GB)
- Oxford BioMedica (United Kingdom) (GB)
- Oxford University Hospitals NHS Trust (GB)
- Cleveland Clinic London (GB)
- William Harvey Research Institute (GB)
- Wythenshawe Hospital (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- University Hospitals Plymouth NHS Trust (GB)
- University of Southampton (GB)
- University College London (GB)
- University of York (GB)
- University of Glasgow (GB)
- University of Birmingham (GB)
- University of Sheffield (GB)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-03-30
- DOI
- https://doi.org/10.1056/nejmoa2415120
- Citations
- 49
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 68.02
Funders
- Boston Scientific Corporation
- British Heart Foundation