Healing Diabetic Foot Ulcers with Topical Timolol Improves Healed Epithelial Integrity

Topical timolol significantly improved skin barrier function in healed DFUs, reducing transepidermal water loss. Although re-ulceration rates were not significantly different, the trend suggests potential benefits. Further studies with larger sample sizes and longer follow-up are needed to confirm these findings and explore transepidermal water loss's predictive value for re-ulceration.

Authors

R. Rivkah Isseroff (ORCID: https://orcid.org/0000-0001-7813-0858)
Anuj Budhiraja
Mirabel Dafinone (ORCID: https://orcid.org/0009-0000-6273-7954)
Rawlings E. Lyle (ORCID: https://orcid.org/0000-0002-0525-2392)
Alisha Mehta
Sara Dahle
Pallas Lim

Institutions

University of California, Davis (US)

Publication Details

Journal: Skin Pharmacology and Physiology
Published: 2025-03-28
DOI: https://doi.org/10.1159/000545357
Citations: 1
Primary Topic: Diabetic Foot Ulcer Assessment and Management
Type: article
Field-Weighted Citation Impact: 1.29

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article

Healing Diabetic Foot Ulcers with Topical Timolol Improves Healed Epithelial Integrity

R. Rivkah Isseroff, Anuj Budhiraja, Mirabel Dafinone, Rawlings E. Lyle et al.

Mar 28, 2025

1 citations

Skin Pharmacology and Physiology

Diabetic Foot Ulcer Assessment and Management

1.29

article

Healing Diabetic Foot Ulcers with Topical Timolol Improves Healed Epithelial Integrity

R. Rivkah Isseroff, Anuj Budhiraja, Mirabel Dafinone, Rawlings E. Lyle, Alisha Mehta, Sara Dahle, Pallas Lim

March 28, 2025article en

1 citations

Abstract

Topical timolol significantly improved skin barrier function in healed DFUs, reducing transepidermal water loss. Although re-ulceration rates were not significantly different, the trend suggests potential benefits. Further studies with larger sample sizes and longer follow-up are needed to confirm these findings and explore transepidermal water loss's predictive value for re-ulceration.

Skin Pharmacology and PhysiologyVol. 38(3)

University of California, Davis (US)

Openalex Percentile: Top 21%

Diabetic Foot Ulcer Assessment and Management

1.29

DOI Source OpenAlex

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