SYNTHESIS OF A NEW DERIVATIVE OF 5-FLUOROURACIL BASED ON 2-CHLORO-N-(4-IODOPHENYL)ACETAMIDE AND STUDY OF ITS BIOLOGICAL ACTIVITY AGAINST CANCER CELLS

In this work, a new compound was synthesized by the reaction of 2-chloro-N-(4-iodophenyl)acetamide with 5-fluorouracil. The process was carried out in two stages, first, the chloroacetylation reaction of 4-iodoaniline was carried out and in the second stage, the new product was synthesized based on the reaction of t

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Publication Details

Journal
Austrian Journal of Technical and Natural Sciences
Published
2025-03-30
DOI
https://doi.org/10.29013/ajt-25-1.2-14-18
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
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article

SYNTHESIS OF A NEW DERIVATIVE OF 5-FLUOROURACIL BASED ON 2-CHLORO-N-(4-IODOPHENYL)ACETAMIDE AND STUDY OF ITS BIOLOGICAL ACTIVITY AGAINST CANCER CELLS

Abdushukurov Anvar Kabirovich, Yusufov Mukhriddin Saidovich, Matchanov Alimjon Davlatboyevich, Ochilov Shohzod Ergash ogli et al.
Austrian Journal of Technical and Natural Sciences
Colorectal Cancer Treatments and Studies
article

SYNTHESIS OF A NEW DERIVATIVE OF 5-FLUOROURACIL BASED ON 2-CHLORO-N-(4-IODOPHENYL)ACETAMIDE AND STUDY OF ITS BIOLOGICAL ACTIVITY AGAINST CANCER CELLS

Abdushukurov Anvar Kabirovich, Yusufov Mukhriddin Saidovich, Matchanov Alimjon Davlatboyevich, Ochilov Shohzod Ergash ogli, Otavaliyev Ibrohim Hamidullo ogli
article en

Abstract

In this work, a new compound was synthesized by the reaction of 2-chloro-N-(4-iodophenyl)acetamide with 5-fluorouracil. The process was carried out in two stages, first, the chloroacetylation reaction of 4-iodoaniline was carried out and in the second stage, the new product was synthesized based on the reaction of t

Austrian Journal of Technical and Natural Sciences
Good health and well-being
Openalex Percentile: Top 91%
Colorectal Cancer Treatments and Studies
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SYNTHESIS OF A NEW DERIVATIVE OF 5-FLUOROURACIL BASED ON 2-CHLORO-N-(4-IODOPHENYL)ACETAMIDE AND STUDY OF ITS BIOLOGICAL ACTIVITY AGAINST CANCER CELLS — Abdushukurov Anvar Kabirovich, Yusufov Mukhriddin Saidovich, et al. · Austrian Journal of Technical and Natural Sciences (2025) | TGRS Research Map | TGRS