Seroprevalence of SARS-CoV-2 antibodies in patients with hematological and oncological diseases in early 2024

The data presented confirm broad variations in SARS-CoV-2 anti-spike IgG levels across patients with different hematological and oncological diseases and highlight the complex interference of cancer biology, immune dysfunction, and treatment-related factors in shaping immune responses. Further research is needed to elucidate the mechanisms underlying these variations in antibody levels. We emphasize the need for regular booster vaccinations in this patient group.

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Publication Details

Journal
Blood Research
Published
2025-03-28
DOI
https://doi.org/10.1007/s44313-025-00067-5
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Seroprevalence of SARS-CoV-2 antibodies in patients with hematological and oncological diseases in early 2024

Lutz Gieselmann, Henning Gruell, Veronica Di Cristanziano, Jannik Stemler et al.
Blood Research
SARS-CoV-2 and COVID-19 Research
article

Seroprevalence of SARS-CoV-2 antibodies in patients with hematological and oncological diseases in early 2024

Lutz Gieselmann, Henning Gruell, Veronica Di Cristanziano, Jannik Stemler, Rosanne Sprute, Jon Salmanton‐García, Oliver A. Cornely, Sibylle C. Mellinghoff, Louise Cremer, Sebastian Herrmann, Theresa Markus
article en

Abstract

The data presented confirm broad variations in SARS-CoV-2 anti-spike IgG levels across patients with different hematological and oncological diseases and highlight the complex interference of cancer biology, immune dysfunction, and treatment-related factors in shaping immune responses. Further research is needed to elucidate the mechanisms underlying these variations in antibody levels. We emphasize the need for regular booster vaccinations in this patient group.

Blood ResearchVol. 60(1)
University of Cologne (DE), Düsseldorf University Hospital (DE), Integrated Oncology (United States) (US), German Center for Infection Research (DE), Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (DE), University Hospital Cologne (DE), Heinrich Heine University Düsseldorf (DE)
Universitätsklinikum Köln
Good health and well-being
Openalex Percentile: Top 91%
SARS-CoV-2 and COVID-19 Research
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Seroprevalence of SARS-CoV-2 antibodies in patients with hematological and oncological diseases in early 2024 — Lutz Gieselmann, Henning Gruell, et al. · Blood Research (2025) | TGRS Research Map | TGRS