Prior chronic periodontitis is associated with chronic rhinosinusitis: A population‐based case‐control study

This study aimed to explore the association of chronic rhinosinusitis (CRS) with prior chronic periodontitis (CP). We performed a case-control study using Taiwan's Longitudinal Health Insurance Database, encompassing a group of 52,733 individuals diagnosed with CRS and 158,199 matched controls without CRS. Our analysis indicated a significantly higher prevalence of prior CP among patients with CRS in comparison with controls (30.49% vs. 22.14%; p < 0.001). The adjusted odds ratio for having CP before the diagnosis of CRS was 1.550 (95% CI = 1.516-1.584), suggesting a moderate association between these conditions. This association was consistent across sex-specific analyses. Of the male sampled patients, the adjusted odds ratio of prior CP for patients with CRS was 1.622 (95% CI = 1.571-1.675) than controls. This study underscores a significant association between CRS and prior CP, suggesting that periodontal health might influence or exacerbate the pathogenesis of sinusitis. The findings advocate for integrated approaches in managing patients with CRS, emphasizing the importance of periodontal health assessments as part of the clinical management of CRS.