The cytotoxic activity of extracts from the Camellia luongii Tran & Le

Camellia luongii Tran et Le. was discovered for the first time in Dinh Hoa District, Thai Nguyen Province, North Vietnam, and was determined as a new species. In 2022, the Camellia luongii Tran & Le was collected from the natural forests of Lung Than, located in the Si Ma Cai district of Lao Cai province, Vietnam. To the best of our knowledge, this is the first report on the cytotoxic activity on cancer cells of HEK-293A, A549, HepG2, MCF7, HT-29, SK-MEL-2, AGS from old leaves, leaf buds, and fruit husks extracts of this species with ethanol 95%. These extracts showed moderate cytotoxic activity on all the tested cell lines with IC50 from 21.75±0.88 to 78.26±3.75 µg/mL.

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Publication Details

Journal
Journal of Pharmacognosy and Phytochemistry
Published
2025-01-01
DOI
https://doi.org/10.22271/phyto.2025.v14.i2d.15298
Primary Topic
Tea Polyphenols and Effects
Type
article
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article

The cytotoxic activity of extracts from the Camellia luongii Tran & Le

William N. Setzer, Do Thi Thuy Van, Nguyễn Huy Hùng, Nguyen Thi Nu Trinh et al.
Journal of Pharmacognosy and Phytochemistry
Tea Polyphenols and Effects
article

The cytotoxic activity of extracts from the Camellia luongii Tran & Le

William N. Setzer, Do Thi Thuy Van, Nguyễn Huy Hùng, Nguyen Thi Nu Trinh, Hoang Thanh Son, Trinh Ngoc Bon, Luong Thu Giang
article en

Abstract

Camellia luongii Tran et Le. was discovered for the first time in Dinh Hoa District, Thai Nguyen Province, North Vietnam, and was determined as a new species. In 2022, the Camellia luongii Tran & Le was collected from the natural forests of Lung Than, located in the Si Ma Cai district of Lao Cai province, Vietnam. To the best of our knowledge, this is the first report on the cytotoxic activity on cancer cells of HEK-293A, A549, HepG2, MCF7, HT-29, SK-MEL-2, AGS from old leaves, leaf buds, and fruit husks extracts of this species with ethanol 95%. These extracts showed moderate cytotoxic activity on all the tested cell lines with IC50 from 21.75±0.88 to 78.26±3.75 µg/mL.

Journal of Pharmacognosy and PhytochemistryVol. 14(2)
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Tea Polyphenols and Effects
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The cytotoxic activity of extracts from the Camellia luongii Tran & Le — William N. Setzer, Do Thi Thuy Van, et al. · Journal of Pharmacognosy and Phytochemistry (2025) | TGRS Research Map | TGRS