Improvement in multiple cognitive domains via combined revascularization by 6 months’ follow-up: a new potential surgical indication in moyamoya disease

Revascularization can selectively reverse cognitive dysfunction by improving cerebral blood flow perfusion in adults with MMD. Combined revascularization may allow more definite hemodynamic improvement than indirect revascularization, leading to more frequent and greater potential improvement in more cognitive domains; however, more studies are needed to confirm this. A population with lower preoperative cognition and good postoperative collateral formation may benefit more from the surgery.

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Publication Details

Journal
Journal of neurosurgery
Published
2025-03-29
DOI
https://doi.org/10.3171/2024.11.jns241932
Primary Topic
Moyamoya disease diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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article

Improvement in multiple cognitive domains via combined revascularization by 6 months’ follow-up: a new potential surgical indication in moyamoya disease

Xiaokuan Hao, Shihao He, Junze Zhang, Xin Lou et al.
1 links
Journal of neurosurgery
Moyamoya disease diagnosis and treatment
article

Improvement in multiple cognitive domains via combined revascularization by 6 months’ follow-up: a new potential surgical indication in moyamoya disease

Xiaokuan Hao, Shihao He, Junze Zhang, Xin Lou, Ning Ma, Yanru Wang, Yu Tao, Ran Duan, Weitao Jin, Xilong Wang, Chaoran Shen, Yongbo Yang, Zhenyu Zhou, Rong Wang, Ziqi Liu, Xinlin Zhou, Jing Gu
article en

Abstract

Revascularization can selectively reverse cognitive dysfunction by improving cerebral blood flow perfusion in adults with MMD. Combined revascularization may allow more definite hemodynamic improvement than indirect revascularization, leading to more frequent and greater potential improvement in more cognitive domains; however, more studies are needed to confirm this. A population with lower preoperative cognition and good postoperative collateral formation may benefit more from the surgery.

Journal of neurosurgeryVol. 143(2)
Capital Medical University (CN), Peking University (CN), Beijing Normal University (CN), Chinese PLA General Hospital (CN), Beijing Tian Tan Hospital (CN), Nanjing Drum Tower Hospital (CN), Peking University International Hospital (CN)
Openalex Percentile: Top 91%
Moyamoya disease diagnosis and treatment
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